The company’s Enzyme Linked Lectin Specific Assay is certainly analogous to the well established enzyme connected immunosorbent assay , and provides been made to bind specifically to carbohydrate structures common to exosomes, however, not to healthy individual cellular components. Each ELLSA plate allows for up to 96 exosome detection tests. Further evaluation of the captured exosomes can be done through recognition molecules such as antibodies connected to a particular biomarker on the exosome.. Aethlon Medical data files provisional patent on behalf of ESI for exosome detection assay Aethlon Medical, Inc. , the pioneer in developing therapeutic filtration devices to handle infectious disease and tumor, announced today that it has filed a provisional patent on behalf of its wholly possessed subsidiary Exosome Sciences, Inc.To clarify which SNP alters GLCCI1 expression directly, we constructed clones of luciferase reporter plasmids containing DNA fragments of rs37972, rs37973, or both . Luciferase reporter actions of the rs37973G clones were decreased, a discovering that was consistent with the haplotypes and indicated that rs37973 can modulate transcriptional activity . We confirmed the allelic variations in rs37973 transcriptional activity by using an unbiased promoter assay . Functional Variant Association We genotyped the functional rs37973 in our replication populations and performed a pooled evaluation of the change in FEV1 after therapy with inhaled glucocorticoids. The rs37973 SNP was associated with significant decrements in FEV1 .