In certain circumstances, HDL could be inflammatory and increase hardening of the arteries, Fonarow said. In other words, prior studies show that in certain patients or using circumstances, the good cholesterol can turn poor and promote the atherosclerosis in fact, he said. These findings might indicate that HDL function becomes altered through the transition to menopause, he said. Further studies are needed to evaluate HDL function in this and other patient populations to help develop additional ways of prevent and treat atherosclerotic cardiovascular disease and stroke, Fonarow stated.. During Menopause, ‘Good’ Cholesterol May Lose Protective Effect on Heart: – FRIDAY, Oct. 16, 2015 – – HDL cholesterol is commonly called the good cholesterol, but new study suggests that it could become harmful to women going right through menopause.‘Over the last one fourth of 2011 and into the first one fourth of 2012, AcelRx completed system verification screening, software validation examining and reprocessing validation examining of our ARX-01 device, furthermore to filing a fresh IND for our ARX-04 product applicant. Shortly, we will be initiating the second Phase 3 study, an active comparator research comparing ARX-01 to the typical of care. These scholarly studies, together with the third and final Stage 3 study to aid an NDA for ARX-01 due to start in the next half of this year, will setup a very exciting 2012 with data from all three research expected by early 2013,’ said Richard King, President and CEO of AcelRx.