It is with a very high risk of serious bleeding complications, including early death from bleeding in the brain. Current treatment of APL is a combination of all-trans plus chemotherapy remission with additional ‘consolidation ‘chemotherapy the the remission, induce followed by a further ATRA with or without oral chemotherapy to maintain remission This approach yields This approach yields complete remission rates of about 90 % and improved event-free survival, with an ‘event ‘as a failure to achieve a complete remission, defined relapse after achieving complete remission or death.. The findings appear in the 11th November edition of Blood.APL accounts for approximately 10 to 15 % of acute myeloid leukemia cases and is the most common in young adults.
, was in the experimental group received arsenic trioxide intravenously for one hour, five days a week, for 5 weeks, with a two week break between courses.. While arsenic trioxide is known by clinicians to be a highly effective treatment for patients with relapsed APL, its benefits already in treatment, after first remission, remained unknown. Until now.
For the study, North American Leukemia Intergroup trial C9710, investigators randomized 481 patients with untreated APL, 15 or older, into two groups. Both groups would receive standard treatment of ATRA and chemotherapy, followed by standard consolidation therapy. One of the groups received two additional 25-day prior to the administration of intravenous arsenic trioxide standard consolidation therapy.Kaiser Family Foundation. 2005 Advisory Board Company and Kaiser Family Foundation. All rights reserved.. She also said House Committee endorses Bill To Lower Medicare the beneficiary prescription drug charges by 3 percent.
A Colorado House the Committee on Thursday voted to to be approved a bill. which would be a max compensable cost provision of the state Medicaid program for prescription drug costs on Medicaid the beneficiary by about 3 percent, Denver Denver Rocky Mountain News report. Bill sponsor Mark changes Cloer said the proposal was the one prescription drug bill this legislature the is not reduced the number of drugs that Medicare recipients may be required.