Placebo Effect Might Help Predict Response to Depressive disorder Treatment: WEDNESDAY.

These individuals were also much more likely to possess fewer depression symptoms if they took the true drug. The scholarly study was published online Sept. 30 in the journal JAMA Psychiatry. The results provide objective evidence that the brain’s own opioid system responds to both antidepressants and placebos, and that variation in this response is associated with variation in symptom alleviation, said first author Dr. Marta Pecina, a study associate professor in Michigan’s section of psychiatry. This finding provides us a biomarker for treatment response in depression – – an objective way to measure neurochemical substances involved with response, she said in a university news discharge. We can envision that by improving placebo effects, we might be able to develop faster-performing or better antidepressants.

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