The trial was conducted by the German AGO Research Group and research centers in Bulgaria.

Aeterna’s AEZS-108 final Phase 2 results in endometrial cancers to end up being presented at ESGO 2011 Aeterna Zentaris Inc. The trial was conducted by the German AGO Research Group and research centers in Bulgaria. AEZS-108, a targeted cytotoxic peptide conjugate, is currently in Phase 1/2 programs in prostate and bladder cancer tumor, and has completed Stage 2 trials in endometrial and ovarian tumor successfully.Blood samples were taken from 550 people of which half suffered from migraines. After analysing the DNA, the team discovered that a mutation of a particular gene was a lot more common in those with the migraine with aura than those without. This mutation means migraine victims will probably have higher levels of a specific amino acid or proteins called homocysteine in the bloodstream. But a diet rich in folate can reduce levels of homocysteine. For most people folate-wealthy foods such as vegetables or folate supplements could not only help ward off migraines but may also help prevent strokes. Dr Lea says it really is too early to state whether folate rich diet programs are the cure-all for people who suffer from migraine.