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Specifically, the document provides suggestions for treatment prioritization and risk-reduction strategies while addressing the next circumstances and conditions that frequently are precursors to, or are concurrent with, a T2DM diagnosis: Management of diabetes and co-existing illnesses or disorders in the prediabetic phase of disease. A hierarchy of measures for the management of high blood sugars control using a strategy that balances age and comorbidities while reducing the undesireable effects of hypoglycemia and excess weight gain. Complications-centric treatment of the overweight or obese patient, as opposed to a body mass index -centric approach, including surgical and procedures for greater weight loss. Management of cardiovascular disease risk factors, hypertension and hyperlipidemia in those individuals with prediabetes or T2DM.