These findings suggest that 5-HT2A antagonists/inverse agonists, such as pimavanserin, could be effective in the treating patients with ADP. ADP represents a major unmet medical need without proven safe and effective therapy, said Uli Hacksell, Ph.D., ACADIA’s LEADER Officer. Physicians often vacation resort to off-label use of antipsychotic medications in individuals with ADP despite their association with elevated mortality and potential worsening of cognitive disturbances. These new findings suggest that pimavanserin may be ideally suited to address the need for a new ADP treatment that’s safe, effective and well tolerated. The PSA test, as well as how it is used to guide patient treatment is highly controversial; nevertheless, the AUA believes that, when provided and interpreted appropriately the PSA test may provide essential info for the diagnosis, pre-treatment staging or risk evaluation and post-treatment monitoring of prostate cancer.At this time, the only methods of birth control for guys are surgical vasectomy – – which is very effective, but everlasting – – and condoms usually, which can be unreliable. Dr. Abraham Morgentaler, a member of the board of directors for the American Sexual Health Association, said, ‘There is a great dependence on a male contraceptive that will not involve minor surgical treatments or condoms.’ That need may be greater in certain countries outside the United States even, where overpopulation is a serious problem, Morgentaler said.