If I let you know, particularly incorrectly, that you have an elevated risk of obtaining a awful disease, that could weigh in your thoughts, that could make you anxious, stated Dr. Robert C. Green of Boston’s Brigham and Women’s Hospital. That may be the filter by which you start to see the rest of your life as you await that disease going to you. It might really up mess you. Every ache and pain, Smith suggested, could be interpreted as the start of the end.Writing in Ophthalmology, the authors report that no associations were found by them between the SNPs and the clinical measures. Furthermore, the response to therapy did not vary by the true number of risk alleles present. The lack of correlation between genotype and response held true whether patients received bevacizumab or ranibizumab and if they were dosed monthly or as needed. Related StoriesMoffitt Malignancy Center study finds link between common gene mutations and tumor immune surveillancePerisylvian polymicrogyria gene foundUCSF-led experts map out melanoma's genetic trajectoriesHagstrom et al note that anti-VEGF therapy is impressive yet there exists a wide range of clinical response and variability in the amount of injections required. ‘Given the impact of genetic factors on disease manifestation and progression, a logical assumption would be that genetic variants play a role,’ they write.