Allikmets. The researchers continue steadily to conduct new studies based on their leads to further understand the triggers because of this gene. ‘This is an area for epidemiologists to study, but as our analysis progresses we should ultimately be in a position to suggest treatment that could keep many folks from going blind,’ he said.. Age-related macular degeneration is definitely triggered, possibly by an infection Age-related macular degeneration, the leading cause of blindness in the elderly, occurs when a common inherited gene variation is definitely triggered, by an infection possibly, according to a fresh study led by researchers at Columbia University Medical Center and the University of Iowa, with a global research team.Bachovchin, Ph.D., professor of biochemistry at Tufts Sackler School of Graduate Biomedical Sciences and colleagues, tested ARI-4175 in colorectal cancer cell lines and in mice with two types of cetuximab-resistant colorectal tumors. Neither cetuximab nor ARI-4175, separately or together, succeeded in killing the cells in lab dishes. In the mice, nevertheless, ARI-4175 blocked tumor growth, and was more lucrative at higher dosages of the drug.