Such a recombination rate of recurrence makes it difficult to determine whether particular recombination occasions explain the recent predominance of El Tor strains. To overcome these limitations, we imposed a strict molecular clock , in agreement with earlier estimates.19 Similarly, we estimate that the ancestor of the classical strains originated between 1843 and 1860, with divergence of the lineage resulting in strain PA1849 occurring between 1797 and 1813, close to the time of the 1st recognized cholera pandemic, in 1817.21 The combined topology and temporal estimations suggest that the 1st five cholera pandemics were due to V. Cholerae possessing a common core genome, each representing a clonal reemergence with few genome-scale mutational differences.When a critically ill person enters the hospital with a suspected infection, clinicians make an effort to determine the reason using tests that may take times to weeks. This may lead to significant delays in appropriate treatment and extended hospital stays, stated David J. Ecker, Ph.D., divisional vice president, R&D for Abbott's Ibis Biosciences business. Abbott's new technology is made to identify infections rapidly, without culture, and provide clinicians with information to prescribe the most effective treatment quickly. An unbiased, expert panel of doctors reviewed the RADICAL research outcomes from samples attained from 420 critically ill patients with suspected severe infections from the uk, France, Belgium, Poland, Germany and Switzerland. Related StoriesMD Anderson research reveals why chemotherapy medicines not effective for most pancreatic cancers patientsGlan Clwyd Hospital N Wales spend money on Esaote's G-Scan MRI device for weight-bearing scanningBoston Children's Medical center selects Vijay G.