Agent orange chemical, dioxin, attacks the mitochondria to cause cancer Researchers with the University of Pennsylvania College of Veterinary Medicine have demonstrated the process where the cancer-causing chemical dioxin attacks the cellular machinery, disrupts regular cellular function and promotes tumor progression. The united team identified for the first time that mitochondria, the cellular sub-systems that convert nutrition and oxygen into cellular energy, are the target of tetrachlorodibenzodioxin, or TCDD femme pharmacie . The study showed that TCDD induces mitochondria-to-nucleus stress signaling, which induces the expression of cell nucleus genes associated with tumor metastasis and promotion. The mechanism the research group has described is directly relevant to understanding incidences of breasts and various other cancers in human populations exposed to these chemical substances.
Screening for cervical cancers and other cancers such as breast and prostate, has clear potential for harms and also benefits, and these must be weighed before a rational decision about screening can be made carefully, wrote Harris and Sheridan, who are professor and assistant professor of medication, respectively, at UNC's School of Medication. They also hold adjunct appointments at UNC's Gillings School of Global Public Health. The analysis noted physicians said these were comfortable with much longer testing intervals, but were worried their patients may not can be found in for annual check-ups if Pap tests, the screening check for cervical cancer, weren’t offered. The problem, Harris said, is certainly that annual Pap lab tests produce more abnormal outcomes leading to additional, invasive tests that itself bring dangers.